By M.D. Esben Kirk
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Additional resources for Acidosis. Clinical Aspects and Treatment with Isotonic Sodium Bicarbonate Solution
Therefore 2 litres of alkaline saline solution were injected intravenously for the third time; this again resulted in considerable improvement, but t h e patient now began to pass large amounts of yellowish offensive fluid per anum. He quickly became exhausted from these diarrheas, chilly and almost pulseless. Therefore 2 more litres of solution were injected intravenously (4th injection) after which the patient soon regained his strength and under the impression of his improvement became quite cheerful.
The patient's consciousness returned, the cadaverous appearance of the body disappeared. Shortly after, however, diarrheas recurred, and 3 hours later the condition was again low. 6 litres) were injected with the same good result. 7 litres) were administered, so that in the course of the first 10 hours a total of 10 litres of fluid was given. The recovery now proceeded rapidly; already 2 days later the patient could enjoy her first pipe of tobacco. She was now transferred to the cholera hospital so as to receive better care and was later discharged from there as well.
Only a few years later, in 1892, Germany and France were again visited by a cholera epidemic which, especially in Hamburg, spread very rapidly and widely. The epidemic left traces in a voluminous literature which treats very thoroughly the results of the parenteral therapy. It is beyond doubt that numerous dramatic recoveries were attained (thus we hear of »zauberhafte Wirkung«), but most of the recoveries were unfortunately shortlived so that the deathrate was hardly much affected. c. 5 litres.
Acidosis. Clinical Aspects and Treatment with Isotonic Sodium Bicarbonate Solution by M.D. Esben Kirk